Recently I noticed that a friend of mine was taking alot of painkillers. She would get up in the morning and take two soluble tablets, then again every three hours. I asked her why she did this as she never complained about being in pain and she freaked out telling me it was none of my business. I looked up the tablets she was taking (Solpadenine) and found out about the effects of codeine based drugs that you can buy over-the-counter in chemists. Here is just a little of what I found out;
In the US the drug has earned the nickname 'Hillbilly heroin'.
Codeine is a short acting opiate drug which belongs to the same family as heroin. Although its effects tend to be milder than heroin, if taken regularly users can become physically dependent on the drug.
Over the Counter (OTC) codeine based analgesic preparations contain small amounts of codeine, usually between 5 and 12.5mg per tablet. The codeine is usually combined with paracetamol (e.g. Solpadeine) or with ibuprofen (an anti-inflammatory drug, e.g. Nurofen Plus).
Herein lies the biggest problem associated with these medications. While codeine is addictive it is not usually physically harmful to those who regularly use the drug. This is similar how people get hooked on cigarettes -- it's the nicotine that's highly addictive, but it's the 4,000 or so chemicals in cigarette smoke that cause, by far, the most damage.
Paracetamol, if taken in sufficiently large quantities (possibly as little as 20 x 500mg tablets a day), is toxic to the liver and can result in irreversible liver failure.
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) and like all NSAIDs, chronic use can result in kidney problems and stomach ulceration.
These ulcers can perforate or bleed, which may require emergency surgery. The vast majority of regular users are unaware of these potentially catastrophic effects.